Zài rènhé changsuo, guanzhòng xiang yào yanzòu shanshuò de jiézòu. Tamen xiang yào ganxìng de biaoyan - dàdan de zhanlan, yiqiè sìhu dou zhèngquè - tamen zànshang keyi tígong zhè zhong tíshì de biaoyan zhe. Tamen pèifú yùndòngyuán, jinguan chongtú de yalì, keyi yíngdé guànjunsài; huò keyi zài baozhuang de tiyùchang nèi jifa guanzhòng de liúxíng geshou; huò xijù yanyuán zài diànshì jiémù zhong de zhèngquè jiechù. Zài rènhé biaoyan fangshì, gongzhòng jìngpèi biaoyan zhe shuí keyi ràng zìji de changhé, bìng gei chu yigè hao de biaoyan, dang ta de zhòngyào.

Jinnián shì 2009 nián, dangshí wo de ayí cóng jiazhou qùshìle. Yóuyú zhàngfu yu tamen youguan, ta bèi mái zài yìndì'annà zhou nán ben dé de Studebaker jiatíng yinmóu zhong. Wo fei dào zhijiage, zule yi liàng che, jihu méiyou zài nán ben dé canting ju háng jiatíng jùhuì. Zài qiutian, wo zài beijing bàifangle lián. Women duì nèiménggu jìnxíngle zhoumò yóulan. Liú zài yigè yuán xíng de xiaowu. Wo ganmàole, yexu shì liúgan. Huí dào meiguó, wo yi zì chuàng de “xin zunyán pàiduì” paole míng ní abo lì si shì zhang. Xuanju jiéguo lìng rén shiwàng.
Zài 2009 nián de zuìhòu yigè yuè, wo kaishi chuàngjiàn yigè míng wèi “BillMcGaughey.Com” de wangzhàn, zuòwéi wo wangzhàn zuòpin de jiaodian. Wo cóng niánqing rén nàli huànle rongcháng de shougao. Gèrén gùshì jiang shì wo de zhuancháng. Rán'ér, liánxù bùduàn de bàoyuàn wo de zìsi. Zhè ji tian, women hen shao zài tóngyi zhang chuángshàng shuìjiào. Lián zài lìng yigè danwèi li you zìji de wòshì. Ta huáiyí wo kenéng huàn you àizibìng. Rán'ér, ta yuè lái yuè duo de hua zài zhongguó, yibiàn yisheng nénggòu jiancè bìngqíng, kàn kàn áizhèng shìfou yijing fanhuí.

Meanwhile, partisans of the Donglin Academy faction, which had been devastated under Wei Zhongxian's influence, established political organizations throughout the Jiangnan region.[5] Chief among these was the Fushe, or Restoration Society, whose members were a new generation of scholars who identified with the old Donglin faction.[6] They succeeded in placing their members into high government posts through the imperial examinations of 1630 and 1631. The reversal of Wei Zhongxian's fortunes resulted in a renewal of the Donglin faction's influence at court, arousing great suspicion from the Chongzhen Emperor.[7] The nomination of Donglin favorite Qian Qianyi for the post of Grand Secretary led to accusations of corruption and factionalism by his rival Wen Tiren. Qian Qianyi was imprisoned on the emperor's orders. Though he was soon released, his status was reduced to that of a commoner and he returned to Jiangnan. Wen Tiren would later become Grand Secretary himself.[8]
Sep 2017: Try the Python implementation of our large-scale GCCA work ‘‘Efficient and Distributed Algorithms for Large-Scale Generalized Canonical Correlations Analysis’’ published at ICDM 2016. The implementation is by Adrian Benton at Johns Hopkins University, who has been doing interesting works in multiview analysis and natural language processing.
As an alternative to the 7F iMN differentiation procedure used in Fig. 7 and S8, iMNs were differentiated from C9-ALS and control iPSC lines using a Dox-NIL system. (a, b) Survival of Dox-NIL iMNs with or without TMX2 reduction by shRNA transduction. Results from two control (a) or two C9-ALS (b) lines were averaged to create the survival curves shown. (c, d) The same iMN data depicted in (b) but separated by individual C9-ALS cell line to show the variability in responses. (e) Representative images of GFP+ (shRNA expressing) C9-ALS iMNs taken during the survival experiments. (f) RNA was harvested from iMN survival experiments at the endpoint and TMX2 mRNA levels were measured by qRT-PCR (normalized to GAPDH levels). For information on the patient lines used and numbers of iMNs analyzed for survival analysis, see Supplementary Table 4.
Our data indicate that motor neurons derived from C9ORF72 and at least a subset of sporadic ALS patients share similar defects in autophagosome formation and glutamate receptor accumulation. Importantly, PAR1 activation by 3K3A-APC can reverse these C9ORF72 and sporadic ALS disease processes in vitro and in vivo (Figure 7). We draw several key conclusions from our findings.
Lín dá líkai gai dìqu hòu, wo yùjiànle an, yigè báirén nu, céngjing gen wo de péngyou hé fángdong ha wéi. Ha wéi de qián shìyou ken·kèlisidì ansen (Ken Christianson) yijing kaishile yigè míng wèi “dí huìjiàn rén” de zìyóu liútong bàozhi, wèi you xìngqù huìjiàn qíta danda di danshen rénshì. Zhèyàng jiù hé ha wéi liánxìle. Ta huàn you yìyù zhèng. Ta dí gege yijing shìtú ba ta zhì yú jingshénbìng yuàn, dàn ta yijing táotuole. Zhè shì yigè you xiyin lì de gùshì. Wo chéngle an dì péngyou, hen kuài ta de liànrén hé wèihunfu. Yijiubaliù nián xiàtian, wo dài ta qù dong jie wojia.
Sep 2017: Try the Python implementation of our large-scale GCCA work ‘‘Efficient and Distributed Algorithms for Large-Scale Generalized Canonical Correlations Analysis’’ published at ICDM 2016. The implementation is by Adrian Benton at Johns Hopkins University, who has been doing interesting works in multiview analysis and natural language processing.
Consistent with the notion that rescuing lysosome numbers in C9ORF72 ALS iMNs might enable autophagic flux even with increased autophagosome formation, the increase in the ratio of GFP+mRFP+ vesicles to GFP–mRFP+ vesicles upon 3K3A-APC treatment was modest compared with the overall increase in GFP+mRFP+ vesicles in both C9ORF72 and sporadic ALS iMNs (Supplemental Figure 2, R and S; 3 C9ORF72 ALS patients and 5 sporadic ALS patients). Thus, 3K3A-APC treatment increases autophagy in C9ORF72 and sporadic ALS iMNs by rescuing both autophagosome formation and lysosome numbers.

King Goujian's army was known for scaring its enemies before battle because its front line consisted of criminals sentenced to death who committed suicide by decapitating themselves.[2] However, in the passage, "越王句踐使死士挑戰,三行,至吳陳,呼而自剄。", the literal translation of "死士" is "soldiers (who are) willing to die", not "criminals sentenced to death". "自剄" means to "commit suicide by cutting one's throat," which was a common way to end one's own life in Ancient China.[3]

Dì sì gè zhèyàng de biànhuà shì jiyú yi xìliè famíng, shoucì chuxiàn zài 19 shìjì zhongyè. Shèying shì dì yigè. Zhèli, jiqì jiang guang jùjiao zài tu fù you guangmin huàxué pin de ban shàng yi chansheng shìjué túxiàng. Zhè zhong jìshù bùtóng yú yiqián de, ta de chanpin shì yigè ganxìng de xíngxiàng, ér bùshì yi zu zì. Shiyòng diàn de jìshù suíhòu: Diànhuà, diànbào, liúshengji hé diànyingyuàn. Zài 20 shìjì, guangbò diànshì xíngshì de diànzi guangbò chuàngzàole zhichí yúlè shídài de dàzhòng chuánbò méiti.


“Zaidi, yuanxiang, quanqu: Zhongguo xin yimin zuozhe zai Xinjiapo” 在地、 原乡、 全球: 中国新移民作者在新加坡  (Local, Original Land, Global: New Chinese Migrant Writers in Singapore) in Kek Lian Wah 郭莲花 and Lim Choon Bee 林春美 (eds.), Jianghu, jiaguo yu Zhongwen wenxue 江湖、家国与中文文学 (The Alternative World, the State, and Chinese literature).  Serdang, Faculty of Modern Languages and Communication, Universiti Putra Malaysia, 2010, pp. 181-193.
Shuo shíhuà, wo zhengfúle hen shao de nurén. Wo hen nán jiejìn tamen. Wo de gè rén youxian shìxiàng ràng wo zouxiàng lìng yigè fangxiàng. Zài shengmìng de zhège jieduàn, wo de shenghuó gongzuò bi jiatíng gèng zhòngyào. Rúguo yigè nánrén keyi zài yigè you shengwàng, fùchu gaoxin de zhíyè zhong jiànlì zìji, nàme huì you henduo nurén huì faxiàn ta you xiyin lì. Hunyin hé jiatíng jiàng zài shìdàng de shíhòu gensuí.
In September 1992, the Fifth Plenary Session of the 14th Central Committee recommended that the main direction in future adjustments of the industrial structure should be to ‘actively promote the tertiary industry’. In 1993, the Central Committee of the Communist Party of China and the State Council officially included the media industry in the tertiary industry in the Decisions on Accelerating Development in the Tertiary Industry, while maintaining this industry’s attributes as a propaganda and administrative institution.
Wo de fánnao yuan yuan méiyou jiéshù. Wèntí zàiyú,Ashley de xiao gongyù li ji manle ta de cáiwù. Yixie wùpin rú yifú shì heisè sùliào dài. Qíta de rén dui zài dìban shàng. a shén lì yeyou dà jiàn jiajù, tèbié shì yigè hòuzhòng de mù zhuo, bìxu zhòngliàng yibai bàng. Zài héfa dì dìfang, yèzhu bèi yaoqiú zuyòng chu wù guì, yibiàn zài zulìn danwèi bèi chaichú hòu, jiang bèi quzhú de zuhù de wùpin baoliú liùshí tian. Rúguo zhifù cúnchú chéngben, zuhù keyi suíhòu shouhuí wùpin. Dànshì, fángdong ye yào zhifù zuche, zhifù gongrén jiazài kache bìng bangzhù banjia.
Yóulǐkǎ (Eureka), Jiālìfúníyàzhōu -- Jì qùnián dì-sì bǎn de zhòngdà shēngjí zhīhòu, Wénlín Yánjiūsuǒ jīntiān yòu fābù le Wénlín 4.1.1 bǎn. Xīn bǎnběn kě zài www.wenlinshangdian.com huòqǔ. Wénlín 4.0 huò 4.1 bǎn de dāngqián yònghù kěyǐ miǎnfèi gēngxīn. Wèile ràng Wénlín Hànyǔ Xuéxí Ruǎnjiàn gèngjiā shíhuì, Wénlín Yánjiūsuǒ yǐjīng xuānbù, wánzhěngbǎn de jiàgé cóng 179 Měiyuán xiàtiáo zhì 99 Měiyuán, shēngjí fèiyòng cóng 49 Měiyuán xiàjiàng zhì 29 Měiyuán. Xīn yònghù zhǐ xū 99 Měiyuán jí kě gòumǎi Wénlín (hán CD, 119 Měiyuán wàijiā yùnfèi); Wénlín 3.x bǎnběn de yònghù gòumǎi kě xiàzài de shēngjí wénjiàn zhǐ xū 29 Měiyuán (hán CD, 49 Měiyuán wàijiā yùnfèi). Xiàzài bǎnběn hé CD bǎnběn dōu kě zài www.wenlinshangdian.com shàng huòdé, yě kě tōngguò Hànyǔ ruǎnjiàn língshòushāng gòumǎi.

(A) Production of Hb9::RFP+ iMNs and survival tracking by time-lapse microscopy. (B and C) Survival of control (CTRL) and C9ORF72 ALS patient (C9-ALS) iMNs with a 12-hour pulse treatment of excess glutamate shown for each individual line separately (B), or for iMNs from all lines in aggregate (C). For B and C, n = 90 iMNs per line for 3 control and 2 C9-ALS lines, iMNs quantified from 3 biologically independent iMN conversions per line. (D) Survival of control and C9ORF72 ALS patient iMNs after withdrawal of neurotrophic factor supplementation. iMNs from all control or C9ORF72 patient lines shown in aggregate. n = 90 iMNs per line for 3 control and 3 C9-ALS lines, iMNs quantified from 3 biologically independent iMN conversions per line. (E and F) Survival of control and sporadic ALS (sALS) patient lines after glutamate treatment (E) or withdrawal of neurotrophic factor supplementation (F). iMNs from all control or C9ORF72 patient lines shown in aggregate. n = 90 iMNs per line for 3 control and 6 (E) or 5 (F) sporadic ALS lines, except sALS6 which had 60 (E) or 40 (F) iMNs counted. iMNs quantified from 3 biologically independent iMN conversions per line. (G–I) Immunofluorescence analysis of total TDP-43 (G) and quantification of the ratio of nuclear to cytoplasmic TDP-43 in control, C9-ALS (H), or sporadic ALS (I) iMNs. Ratio of nuclear to cytoplasmic TDP-43 in individual iMNs treated with 10 nM inactive 3K3A-APC or 3K3A-APC for 6 days. iMNs from 2 controls and 2 C9-ALS patients (H) or 4 sporadic ALS patients (I) were quantified. n = 30 (controls), 30 (C9-ALS), or 36 (sporadic) iMNs per line per condition from 2 biologically independent iMN conversions of 2 control, 2 C9-ALS, or 4 sporadic ALS lines were quantified. Each gray circle represents a single iMN. Median ± interquartile range. Unpaired Mann-Whitney test. Scale bars: 5 μm. Dotted lines outline the nucleus and cell body. For iMN survival experiments, significance was measure by 2-sided log-rank test using the entire survival time course. The day of differentiation stated on each panel indicates the day of differentiation on which the experimental treatment or time course was initiated.
(A) Production of Hb9::RFP+ iMNs and survival tracking by time-lapse microscopy. (B and C) Survival of control (CTRL) and C9ORF72 ALS patient (C9-ALS) iMNs with a 12-hour pulse treatment of excess glutamate shown for each individual line separately (B), or for iMNs from all lines in aggregate (C). For B and C, n = 90 iMNs per line for 3 control and 2 C9-ALS lines, iMNs quantified from 3 biologically independent iMN conversions per line. (D) Survival of control and C9ORF72 ALS patient iMNs after withdrawal of neurotrophic factor supplementation. iMNs from all control or C9ORF72 patient lines shown in aggregate. n = 90 iMNs per line for 3 control and 3 C9-ALS lines, iMNs quantified from 3 biologically independent iMN conversions per line. (E and F) Survival of control and sporadic ALS (sALS) patient lines after glutamate treatment (E) or withdrawal of neurotrophic factor supplementation (F). iMNs from all control or C9ORF72 patient lines shown in aggregate. n = 90 iMNs per line for 3 control and 6 (E) or 5 (F) sporadic ALS lines, except sALS6 which had 60 (E) or 40 (F) iMNs counted. iMNs quantified from 3 biologically independent iMN conversions per line. (G–I) Immunofluorescence analysis of total TDP-43 (G) and quantification of the ratio of nuclear to cytoplasmic TDP-43 in control, C9-ALS (H), or sporadic ALS (I) iMNs. Ratio of nuclear to cytoplasmic TDP-43 in individual iMNs treated with 10 nM inactive 3K3A-APC or 3K3A-APC for 6 days. iMNs from 2 controls and 2 C9-ALS patients (H) or 4 sporadic ALS patients (I) were quantified. n = 30 (controls), 30 (C9-ALS), or 36 (sporadic) iMNs per line per condition from 2 biologically independent iMN conversions of 2 control, 2 C9-ALS, or 4 sporadic ALS lines were quantified. Each gray circle represents a single iMN. Median ± interquartile range. Unpaired Mann-Whitney test. Scale bars: 5 μm. Dotted lines outline the nucleus and cell body. For iMN survival experiments, significance was measure by 2-sided log-rank test using the entire survival time course. The day of differentiation stated on each panel indicates the day of differentiation on which the experimental treatment or time course was initiated.
90 Niándài chu, fanduì zìyóu màoyì chéngwéi wo de shìyè. Tongguò wo zhiqián duì duan zhouqí lìfa de xìngqù, wo biàn dé yu shuyú UAW“xin fangxiàng” yùndòng de shèngbaoluó fútè gongchang de yixie gonghuì chéngyuán you liánxì. Tamen yu mòxige de fútè gongrén you liánxì, tamen zhèngzài nulì zhengqu dúlì de gonghuì dàibiao quán. 1992 Nián 6 yuè, zài Cuautitlan Ford gongchang juxíng de gonghuì xuanju zhong, wo chéngwéi yi míng wàiguó rén quán guancháyuán, xiàng meiguó can yìyuán baoluó·wéi si dùn (Paul Wellstone) fasòngle yi fèn bàogào.
Women méiyou háizi, yinwèi wo de qizi you zigong nèi mó yì wèi zhèng, daozhì bù yù zhèng, yexu shì yinwèi ta zài dì yi cì hunyin zhong shiyòng bìyùn yào. Women qùle dàxué de zhensuo kàn yixué shàng kenéng huì zuò shénme. Ka luó er faxiàn zhège zhengti de jingyàn lìng rén yànwù, chìluoluo de shùfù zài jianchá tái shàng de shèbèi shàng. Ta zhizé wo yaoqiú ta huáiyùn.
Zài yigè yuánshi shèhuì, zhiyou dàxíng jigòu, rú zhèngfu huò sìmiào de jìsi cái nénggòu fùdan zhège yìshù zhong de rén. Wénjiàn jìlù shuìshou, fal? hétóng, zongjiào yíshì, yijí jigòu xuyào yùnzuò de qíta wénjiàn huò xìnxi. Xiàng hòulái zhongguó cháodài de rújia xuézhe yiyàng, zhangwò xiezuò jìqiao de aijí huò su mei er guanli zhe chángcháng zài dìguó guanliáo tixì zhong zhànyou gaowèi. Tamen huòdé shumiàn zhishì chéngwéi tèquán hé quánlì de láiyuán. Huòdé shìzì de kùnnán yìwèizhe zhè zhong quánlì jiang zhangwò zài shaoshù rén de shouzhong.
Wénlín Hànyǔ Xuéxí Ruǎnjiàn 4.0 bǎn bāokuò le yī zhǒng chuàngxīn de héxīn jīchǔ jìshù hé chuàngzuò gōngjù, yòngyú shūrù, chuánshū bìng xiǎnshì Unicode zhōng wèi bāohán de xīn zì, yìtǐzì, shēngpì zì. Zìxíng Miáoshù Yǔyán (CDL) shì yī zhǒng chǔlǐ Zhōngwén, Rìwén hé Hánwén (CJK) zìtǐ hé shùjù de gèng jǐncòu, gèng gāoxiào, gèng zhǔnquè de fāngfǎ, tā de chūxiàn jiějué le cāozuò xìtǒng hé xiǎoxíng shèbèi píngtái kāifāzhěmen xīwàng jiějué de wèntí. Wénlín CDL kě chǔlǐ 3000 ge zuì chángyòng zì, xiàoguǒ yōuyú Unicode, tóngshí wúxiàn kuòzhǎn le zìfújí, wèi shìjiè qítā de yònghù tígōng le gèngduō zìyóu hé biànlì. Yǔnxǔ zhōngduān yònghù zài 4 bǎnběn zhōng shǐyòng CDL jìshù, zhè wèi géxīn CJK gōngnéng pūpíng le dàolù. “Yīdàn zuìzhōng yònghù kāishǐ shǐyòng 4.0 bǎnběn de CDL chuàngzuò gōngjù, héxīn jīchǔ jíchéng de chǎngjǐng biàn de gèng qīngxī, wǒmen xīwàng wǒmen de shòuquán yèwù nénggòu yīncǐ dédào xiǎnzhù tuòzhǎn,” yíngxiāo fùzǒngcái Mǎkè Luóbùlǐ (Mark Roblee) rúcǐ shuōdào.

The majority of the scholarly analyses of convergence under the culture-oriented perspective have focused on its effects on routines, skills and roles. Several studies indicate that media convergence has changed the routine of information gathering, editing and reporting within newsrooms (Phillips et al., 2009); made journalistic practices considerably stressful with the emergence of multiskilling (Wallace, 2013) and posed severe challenges on the traditional roles of news media, such as ‘gatekeeper’ (Williams and Delli Carpini, 2000) and ‘agenda-setter’ (Quandt and Singer, 2009), as the tendency of convergence between professional- and user-produced content becomes increasingly appreciable. Other studies that employed the same approach indicate that although journalists are confronted with multiple challenges, they do not necessarily take a negative stance to evaluating media convergence. Accordingly, the degree of media convergence (Saltzis and Dickinson, 2008) and size of a media organisation (Mishra, 2014) can affect the perceptions journalists have on convergence journalism, thereby affecting their attitude towards media convergence.
 “Jiu qiaoxiang de zhuanxing: 1978 zhi 2000 nian zhijian lisan huaren dui Panyu de yingxiang” 旧侨乡的转型:1978至2000年之间离散华人对番禺的影响   (The Transformation of Old Qiaoxiang: Chinese Diaspora’s Impact on Panyu, 1978-2000) in Tan Chee Beng 陈志明, Ding Yuling 丁毓玲 and Wang Lianmao 王连茂 (eds.), Kuaguo wangluo yu Huanan qiaoxiang: wenhua, rentong he shehui bianqian 跨国网络与华南侨乡:文化、认同和社会变迁  (Transnational Networks and Qiaoxiang Areas in South China:  Cultural, Identity and Social Change).  Hong Kong: Hong Kong Institute of Asia-Pacific Studies香港亚太研究所, Chinese University of Hong Kong, 2006 , pp. 303-343.
Zài yigè yuánshi shèhuì, zhiyou dàxíng jigòu, rú zhèngfu huò sìmiào de jìsi cái nénggòu fùdan zhège yìshù zhong de rén. Wénjiàn jìlù shuìshou, fal? hétóng, zongjiào yíshì, yijí jigòu xuyào yùnzuò de qíta wénjiàn huò xìnxi. Xiàng hòulái zhongguó cháodài de rújia xuézhe yiyàng, zhangwò xiezuò jìqiao de aijí huò su mei er guanli zhe chángcháng zài dìguó guanliáo tixì zhong zhànyou gaowèi. Tamen huòdé shumiàn zhishì chéngwéi tèquán hé quánlì de láiyuán. Huòdé shìzì de kùnnán yìwèizhe zhè zhong quánlì jiang zhangwò zài shaoshù rén de shouzhong.
“Locating Chinese New Migrants in National and Ethnic Contexts: The Singapore Case,” presented at the book launch of Lee Guan Kin (ed.), Demarcating Ethnicity in New Nations: Cases of the Chinese in Singapore, Malaysia, and Indonesia 新马印华人:族群关系与国家建构(Singapore: Singapore Society of Asian Studies, Konrad-Adenauer-Stiftung, 2006)and public talk on “Culture and Nation: Ethnic Chinese in Singapore, Malaysia, and Indonesia” 新马印华人:文化与国家  at the National Library, Singapore, organized by Singapore Society of Asian Studies, Kondrad-Adenauer-Stiftung, and Singapore’s National Library Board, 17 December 2006.
Shangjia kenéng yijing dì yi cì shiyòng ta. Tamen zài fangwèn mòsheng hé yáoyuan dì dìfang de jinglì cìjile yuyán, zongjiào, xísú hé sixiang zhi jian de bijiào. Zhège duan shouxie de jiaoben chuàngzàole yi zhong gèngjia jinglì chongpèi hé tànsuo de shèhuì lèixíng. Yixie xúnwèn zhe shì fazhan zìji de sixiang xìtong de zhéxué jia. Suízhe xiezuò zhishì guangfàn chuánbò, qí shìjué biaojì chéngwéi hàoqí xin de duìxiàng, yóuqí shì zài jùyou qiángliè koutóu chuántong de shèhuì. Zhè zhong shèhuì cúnzài yú 5 shìjìde xilà chéngbang. Hé ma shi, jì dé bù dú, shì xilà rén liánhé de wénhuà juzhèn. Rán'ér, xiàng Hesiod,Aeschylus hé Sophocles zhèyàng de zuòjia ye zài xiànchang.
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